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目的观察顾氏喉科祖传验方碧雪散治疗复发性口腔溃疡的临床疗效。方法将115例患者随机分为碧雪散组(58例)和锡类散组(57例),分别予碧雪散、锡类散局部外敷;两组均治疗28天,观察临床疗效及中医症状体征分级量化评分变化。结果碧雪散组、锡类散组总有效率分别为98.2%、86.0%;组间临床疗效比较,差异有统计学意义(P<0.05)。两组治疗前后组内比较,中医症状体征积分差异均有统计学意义(P<0.05);组间治疗后比较,中医症状体征积分差异有统计学意义(P<0.05)。结论顾氏喉科祖传验方碧雪散局部外敷可有效用于复发性口腔溃疡的临床治疗。
Objective To observe the clinical efficacy of Gu’s throat branch ancestral experience Fang Bixue powder in the treatment of recurrent oral ulcer. Methods One hundred and fifteen patients were randomly divided into two groups: Bixue powder group (58 cases) and tin group (57 cases), with Baxi powder and tin powder separately. The two groups were treated for 28 days, and the clinical curative effect and TCM Symptoms and signs grading quantitative score changes. Results The total effective rates of Bixue powder group and tin powder group were 98.2% and 86.0%, respectively. There was significant difference between the two groups in clinical efficacy (P <0.05). There were significant differences in symptom and symptom scores between the two groups before and after treatment (P <0.05). After treatment, there were significant differences in symptom and symptom scores between two groups (P <0.05). Conclusion Gu’s throat branch ancestral experience Fang Bixue scattered external application can be effectively used for the treatment of recurrent oral ulcers.