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花楸属植物S.commixta皮在东方医学中用作强壮药和止咳药。前期研究表明该植物甲醇提取物显示独特的血管舒张作用,但机制尚不清楚。作者研究了该植物皮的甲醇提取物(MSC)对雄性SD大鼠离体主动脉环的作用及作用机制。结果显示,1)MSC(1×10-7~1×10-4g/mL)对去氧肾上腺素预处理(3
The S. commixta peel is used as a strong drug and cough suppressant in oriental medicine. Previous studies have shown that the plant methanol extract shows a unique vasodilation effect, but the mechanism is not yet clear. The authors studied the effects of methanol extract (MSC) of this plant skin on the isolated aortic rings of male SD rats and the mechanism of action. The results showed that 1) MSC (1×10-7~1×10-4g/mL) pretreatment with phenylephrine (3