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目的调查医院男性泌尿生殖道感染患者支原体感染及耐药情况,为临床用药提供依据。方法对291例男性泌尿生殖道炎症患者分泌物进行解脲脲原体(Uu)和人型支原体(Mh)培养及药敏试验。结果 291例患者中,137例支原体检测阳性,检出率为47.1%。其中Uu阳性134例(46.0%),Mh阳性39例(13.4%),Uu+Mh混合感染36例(12.4%)。药敏结果表明,支原体对强力霉素和美满霉素较敏感;对大环内酯类抗菌药物耐药率差异较大,其中对交沙霉素耐药率接近20%;对3种喹诺酮类敏感率均<35%,氧氟沙星耐药率最高;多重耐药现象明显。结论本地区男性泌尿生殖道感染患者中支原体感染存在普遍,以Uu为感染主,支原体对多种抗菌药物存在耐药,药敏试验能为男性泌尿生殖道感染患者合理用药提供支持。
Objective To investigate the prevalence of mycoplasma infection and drug resistance in male genitourinary tract infection in hospital and provide evidence for clinical use. Methods The secretion of UU and Mh from 291 male patients with genitourinary tract inflammation were tested for drug sensitivity. Results Among the 291 patients, 137 cases were positive for mycoplasma, the detection rate was 47.1%. Among them, 134 (46.0%) were positive for Uu, 39 (13.4%) were positive for Mh and 36 (12.4%) were mixed for Uu + Mh. Susceptibility results showed that mycoplasma was more sensitive to doxycycline and minocycline, macrolide antibacterial drug resistance rates were quite different, of which josamycin resistance rate was close to 20%; three quinolones Sensitive rate <35%, ofloxacin the highest rate of resistance; multi-drug resistance was obvious. Conclusions Mycoplasma infection is common in male genitourinary tract infections in our region, mainly Uu. Mycoplasma is resistant to various antimicrobial agents. The drug susceptibility test can provide support for rational use of drugs in male genitourinary tract infections.