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北京大学第三医院研究人员发现,浓度为20μg/mL淫羊藿苷能够增加MTT的吸光度值,刺激人成骨细胞增殖,并且能显著提高人成骨细胞的碱性磷酸酶活性。碱性磷酸酶是参与骨代谢的重要蛋白质,被认为是细胞外基质成熟的早期标志,碱性磷酸酶的活性可以代表成骨细胞的早期分化水平。因此,
Researchers at the Third Hospital of Peking University found that icariin at a concentration of 20 μg/mL can increase the absorbance of MTT, stimulate the proliferation of human osteoblasts, and can significantly increase the alkaline phosphatase activity of human osteoblasts. Alkaline phosphatase is an important protein involved in bone metabolism and is considered as an early marker of maturation of extracellular matrix. The activity of alkaline phosphatase can represent the early differentiation level of osteoblasts. therefore,