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目的 :探讨临床T1~ 2 N0 M0 乳腺癌患者腋窝淋巴结转移 (ALNM)的高危因素。方法 :采用回顾性病例对照研究 ,对 2 5 6例乳腺癌患者进行单因素及多因素Logistic回归分析。 结果 :多因素分析显示微淋巴管浸润、肿瘤大小、肿瘤部位、癌周浸润、间质浸润等 5个指标进入Logistic回归方程 ,P值分别为 0、0 .0 0 5 6、0 .0 2 3 9、0 .0 2 2 5和0 .0 30 1。结论 :微淋巴管浸润、肿瘤大小、肿瘤部位、癌周浸润、间质浸润等为临床T1~ 2 N0 M0 乳腺癌患者ALNM的高危因素 ;了解高危因素 ,有助于临床准确判断ALNM情况。
Objective: To investigate the risk factors of axillary lymph node metastasis (ALNM) in patients with T1 ~ 2 N0 M0 breast cancer. Methods: A retrospective case-control study of 256 cases of breast cancer patients by univariate and multivariate Logistic regression analysis. Results: Multivariate analysis showed that 5 indicators, including lymphatic invasion, tumor size, tumor location, perivascular invasion and interstitial infiltration, entered Logistic regression equation with P values of 0,0. 0 5 6,0. 0 2 3 9,0 .0 2 2 5 and 0 .0 30 1. Conclusion: Lymphatic invasion, tumor size, tumor location, perivascular invasion and interstitial infiltration are the risk factors for ALNM in T1 ~ 2 N0 M0 breast cancer patients. Understanding the risk factors may help to determine the clinical status of ALNM accurately.