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肝纤维化是肝脏受到各种慢性损伤的愈合反应,表现为细胞外基质(ECM)大量合成、分泌,而降解绝对或相对不足,使ECM在肝脏内弥漫性沉积。肝纤维化是各种慢性肝病共同的病理过程,并是影响预后的重要因素。近10多年对肝纤维化的形成机制研究取得了令人鼓舞的进展,肝纤维化可以逆转这
Liver fibrosis is the healing response of the liver to a variety of chronic injuries, manifested as a large number of extracellular matrix (ECM) synthesis, secretion, and degradation is absolutely or relatively insufficient, so that the ECM is diffusely deposited in the liver. Liver fibrosis is a common pathological process of various chronic liver diseases, and it is an important factor that affects the prognosis. Over the past 10 years, encouraging progress has been made in the study of the mechanism of liver fibrosis formation, and liver fibrosis can reverse this