报道50例SLE患者的10年(1980年～1990年)随访结果。10年的生存率情况,以发病时间计算,其一年、五年、十年生存率分别为98％、98％、84％,以确诊时间计算,则分别为98％、86％、76％。本组患者十年中死亡12例(24％),感染与肾功能衰竭为两大主要死因,分别占33％及33％。74％存活的患者能很好工作与生活,12例患者病情缓解,平均缓解时间4年(2年～9年)随访,结果表明SLE的早期诊断,以及预防感染与肾衰是进一步降低SLE死亡率的两大关键。 Reported 50 patients with SLE in 10 years (1980 ~ 1990) follow-up results. The 10-year survival rates were 98%, 98% and 84% respectively according to the time of onset and 98%, 86% and 76% respectively according to the diagnosis time. . The patients died in 10 years (24%), infection and renal failure were the two major causes of death, accounting for 33% and 33%. 74% of surviving patients were able to work and live well, 12 patients were relieved, and the mean response time was 4 years (ranged from 2 years to 9 years). The results showed that early diagnosis of SLE and prevention of infection and renal failure further reduced SLE death Rate of the two key.