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目的:研究米非司酮配伍米索前列醇中期引产的临床效果。方法:16~27周妊娠要求引产妇女270例,其中研究组米非司酮配伍米索前列醇120例,对照组水囊宫腔置入结合催产素静点150例。结果:研究组与对照组24h内引产成功率分别为97.5%、80%(P<0.01);48h内引产成功率分别为99.17%、92%(P<0.05)。结论:16~27周妊娠中期引产,米非司酮配伍米索前列醇效果优于水囊引产。
Objective: To study the clinical effect of mifepristone and misoprostol on mid-term induction of labor. Methods: A total of 270 pregnant women were enrolled in the study during pregnancy from 16 to 27 weeks. Among them, 120 cases were treated with mifepristone and misoprostol in the study group, and 150 cases were treated with intravenous injection of oxytocin in the control group. Results: The success rates of induction of labor within 24 h in study group and control group were 97.5% and 80%, respectively (P <0.01). Success rates of induced labor within 48 hours were 99.17% and 92% (P <0.05) respectively. Conclusion: Induction of mifepristone and misoprostol over 16-27 weeks of gestation is better than that of hydrogel induction of labor.