糖尿病视网膜病变(diabetic retinopathy,DR)是糖尿病最常见和最严重的并发症之一。目前,DR的发病机制尚不明确,但近年来研究表明,血管生成促进因子与DR新生血管的发生、发展密切相关,是导致视网膜新生血管形成的主要致病因子。本文就血管生成促进因子在DR新生血管形成中的作用进行综述。 Diabetic retinopathy (DR) is one of the most common and serious complications of diabetes mellitus. At present, the pathogenesis of DR is not yet clear, but in recent years, studies have shown that angiogenesis promoting factor is closely related to the occurrence and development of DR neovascularization and is the main causative factor of retinal neovascularization. This article reviews the role of angiogenic promoters in DR neovascularization.