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目的分析中西医结合内镜下综合介入治疗联合放疗治疗老年食管癌的临床疗效。方法回顾性分析60例局部中晚期老年患者不能手术的食管癌患者的临床资料。试验组28例局部中晚期老年患者采用内镜下介入治疗辅助中医联合放疗,放疗总剂量60~70 Gy。对照组32例接受单纯放疗,总剂量同试验组。比较两组的疗效和耐受性。结果试验组和对照组的有效率分别为82%和69%,差异无统计学意义(P>0.05);不良反应发生率试验组较对照组降低(P<0.05)。结论中西医结合内镜下综合介入治疗联合放疗治疗老年食管癌疗效肯定,同时可改善患者的生活质量,减轻放化疗的不良反应,患者耐受性好,值得临床进一步推广,但最终结论有待于进一步扩大样本量进行临床随机对照研究。
Objective To analyze the clinical efficacy of integrated traditional Chinese and western medicine combined with endoscopic treatment with radiotherapy in the treatment of esophageal cancer in the elderly. Methods The clinical data of 60 patients with esophageal cancer who were inoperable in the middle-late advanced stage were retrospectively analyzed. In the experimental group, 28 cases of locally advanced elderly patients underwent endoscopic interventional radiotherapy combined with radiotherapy. The total dose of radiotherapy was 60-70 Gy. Control group, 32 patients received radiotherapy alone, the total dose of the same test group. The efficacy and tolerability of the two groups were compared. Results The effective rates of the experimental group and the control group were 82% and 69%, respectively, with no significant difference (P> 0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group (P <0.05). Conclusion Integrated traditional Chinese and Western medicine combined with endoscopic radiotherapy for the treatment of elderly esophageal cancer is positive, and can improve the quality of life of patients and reduce the adverse reactions of radiotherapy and chemotherapy, patients with good tolerance, it is worth further clinical promotion, but the final conclusion to be Further expand the sample size for clinical randomized controlled study.