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本文比较了单用H、HOC加减及HOAP方案治疗急性非淋巴细胞性白血病140例的疗效。HOAP及HOC的疗效(53.4％、56.00％)显著高于单用H组(25％),P<0.05,而HOAP与HOC相比,P>0.05。但HOAP比HOC更易引起严重并发症。建议对不增生型白血病以单用三尖杉为宜,对白细胞、血小板比较低且临床上有严重感染及出血的患者,以HOC加减为宜,对白细胞明显增高者,以HOAP为宜。
This article compares the treatment of 140 cases of acute non-lymphocytic leukemia with H, HOC addition and subtraction and HOAP alone. The efficacy of HOAP and HOC (53.4%, 56.00%) was significantly higher than that of H group (25%) alone, P <0.05, while HOAP was significantly higher than HOC (P> 0.05). But HOAP is more likely to cause serious complications than HOC. Proposed non-proliferation of leukemia single Cephalotaxal is appropriate, the white blood cells, platelet ratio is relatively low and clinically severe infection and bleeding in patients with HOC addition and subtraction appropriate, significantly higher for leukocytes to HOAP is appropriate.