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目的观察抑亢丸治疗弥漫性甲状腺肿伴甲状腺机能亢进症(Graves病)的临床疗效。方法60例Graves病患者随机分为抑亢丸加丙基硫氧密啶组和丙基硫氧嘧啶组。观察治疗前后甲状腺功能、甲状腺肿大及突眼的变化情况。结果两组在改善甲状腺功能方面结果相似(P>0.05),抑亢丸加丙基硫氧嘧啶组对突眼及甲状腺肿大的有效率优于丙基硫氧嘧啶组(P<0.05)。结论抑亢丸联合丙基硫氧嘧啶治疗Graves病可提高疗效。
Objective To observe the clinical efficacy of Yikangwan in the treatment of diffuse goiter complicated with hyperthyroidism (Graves’ disease). Methods Sixty patients with Graves’ disease were randomly divided into YKK plus propylthiouracil group and propylthiouracil group. Observed before and after treatment of thyroid function, thyroid enlargement and exophthalmos changes. Results The two groups had similar results in improving thyroid function (P> 0.05). The effective rate of prophylaxis and thyroid enlargement was better than that of propylthiouracil group (P <0.05). Conclusion YKK combined with propylthiouracil can improve the therapeutic effect on Graves’ disease.