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通过使纯合子雄鼠与杂合子雌鼠交配的方法获得先天性无胸腺大鼠(rnu/rnu)。裸鼠的血淋巴细胞计数随着年令减少,而嗜中性白细胞,嗜酸性白细胞和单核细胞数却明显增加。裸鼠的血清IgM水平在杂交鼠正
Congenital athymic rats (rnu / rnu) were obtained by mating homozygous males with heterozygous females. Nude mice blood lymphocyte count decreased with the year, and neutrophils, eosinophils and monocytes increased significantly. Serum IgM levels in nude mice were positive in the hybrid mice