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目的 :研究川乌与白芍 (以下简称乌芍 )配伍前后对大鼠佐剂关节炎的影响。方法 :川乌、白芍不同比例水煎液通过灌胃给药 ,应用于大鼠佐剂性关节炎的原发性、继发性预防和治疗 3种实验模型 ,观察配伍前后对大鼠原发性、继发性佐剂关节炎的预防和治疗作用。结果 :乌芍配伍前后对原发性关节炎都有显著的治疗作用 ,对继发性关节炎 ,白芍和乌芍配伍组有显著的预防作用 ,川乌的作用较弱 ,川乌、白芍各药单用无显著治疗作用 ,各配伍组具有显著的治疗作用。结论 :乌芍配伍后对大鼠继发性佐剂关节炎的疗效显著优于单味药 ,表现出明显的配伍优势。
Objective : To study the effect of Chuanwu and Baiji (hereinafter referred to as Wuyi) on adjuvant arthritis before and after compatibility. METHODS: Different proportions of Chuanwu and Baizhu decoction were administered by intragastric administration. They were applied to the primary and secondary prevention and treatment of adjuvant arthritis in rats. Three kinds of experimental models were observed before and after compatibility. Prevention and treatment of secondary and secondary adjuvant arthritis. RESULTS: Before and after the combination of Chinese black peony, it has a significant therapeutic effect on primary arthritis. It has a significant preventive effect on secondary arthritis, white peony, and black peony compatibility groups. Chuanwu has a weaker effect. There was no significant treatment effect for each drug in each drug, and each drug group had a significant therapeutic effect. Conclusion : The effect of Wuqi compatibility on secondary adjuvant arthritis in rats is significantly better than that of single herb. It shows obvious compatibility advantages.