近年来,我国儿童手足口病发病率较高,且呈流行趋势,病情发展快,重症病例较多,而重症手足口病临床早期表现不典型,首诊医师易忽略。但病情进展迅速,一旦出现脑干脑炎及神经源性肺水肿并发症,可短期内死亡,给进一步治疗造成困难。因此,手足口病重症的临床早期识别诊断尤为重要。1资料与方法 In recent years, the incidence of hand-foot-mouth disease in children in our country is high, and the epidemic trend is rapid. The disease develops fast and the number of severe cases is high. However, the clinical manifestations of severe hand-foot-mouth disease are not typical at the early stage. However, the rapid progression of the disease, in case of brain stem encephalitis and neurogenic pulmonary edema complications may be short-term death, resulting in further treatment difficulties. Therefore, the diagnosis of HFMD is very important in early clinical diagnosis. 1 data and methods