目的:对女性子宫颈疾病病变的危险因素进行分析。方法:通过VIA和VILI以及阴道镜检查初步筛查选取苍南地区20~55岁之间的女性子宫颈疾病患者824例作为研究对象。采取引发子宫颈疾病的主要病毒人乳头状瘤病毒(HPA)检测技术,并对子宫颈疾病的影响因素进行Logistic分析。根据分析结果分为两组,实验组给予早期干预,对照组不给于早期干预,随访观察宫颈癌的发病和预后情况。结果:24岁以下以及30~34岁之间的HPA感染率较高,30~39岁之间的HR-HPV的感染率较高。Logistic多因素分析显示,苍南地区的女性子宫颈疾病与初次性生活年龄较早、孕次以及性伴侣数等因素有关。与教育程度、饮食等可能有关,与吸烟饮酒无关。早期干预可以降低患者宫颈癌的转变,并有助于宫颈癌的预后。结论:要加强苍南地区女性的HPV病毒检测,早发现早治疗,降低宫颈疾病的发病率。 Objective: To analyze the risk factors of cervical lesions in women. METHODS: A total of 824 female patients with cervical diseases between the ages of 20 and 55 in Cangnan were enrolled in this study through VIA, VILI and primary colposcopy screening. To take the main virus caused by cervical disease, human papilloma virus (HPA) detection technology, and factors affecting cervical disease by Logistic analysis. According to the analysis results are divided into two groups, the experimental group given early intervention, the control group did not give early intervention, follow-up observation of cervical cancer incidence and prognosis. Results: The prevalence of HPA infection was significantly lower among patients under 24 and between 30 and 34 years old. HR-HPV infection rates were higher among 30-39 years old. Logistic multivariate analysis showed that female cervical diseases in Cangnan were related to the age at first sexual life, pregnancy time and the number of sexual partners. And education, diet may be related to smoking and drinking has nothing to do. Early intervention can reduce the cervical cancer in patients with changes and contribute to the prognosis of cervical cancer. Conclusion: It is necessary to strengthen the detection of HPV in Cangnan women. Early detection and early treatment of cervical cancer can reduce the incidence of cervical diseases.