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目的:比较分析糖皮质激素两种给药方式治疗婴幼儿哮喘急性发作的临床效果。方法:将我院2013年1月至2016年12月收治的48例婴幼儿哮喘急性发作患者,将其随机分为研究组和对照组,每组各为24例,两组均给予常规治疗,对照组采用口服醋酸泼尼松片治疗,研究组采用布地奈德混悬液雾化吸入治疗,对两组患儿的临床效果进行比较。结果:研究组总有效率为91.67%,对照组总有效率为83.33%,研究组患儿总有效率略高于对照组,但比较无显著差异(P>0.05);研究组患儿控制率为66.67%,对照组患儿控制率为45.83%,研究组患儿临床控制率明显高于对照组(P<0.05),比较差异具有统计学意义。结论:雾化吸入治疗婴幼儿哮喘急性发作疗效与口服药物相比基本相同,但雾化吸入临床控制优于口服给药,能对患者的临床症状进行快速缓解,值得在临床上推广使用。
Objective: To compare the clinical effects of two administrations of glucocorticoids on acute asthma in infants and young children. Methods: Forty-eight cases of acute exacerbation of asthma in our hospital from January 2013 to December 2016 were randomly divided into study group and control group, with 24 cases in each group. Both groups were given routine treatment, The control group was treated with prednisone acetate oral administration. The study group was treated with inhalation of budesonide suspension, and the clinical effects of the two groups were compared. Results: The total effective rate was 91.67% in the study group and 83.33% in the control group. The total effective rate in the study group was slightly higher than that in the control group, but there was no significant difference (P> 0.05). The control rate Was 66.67%. The control rate in control group was 45.83%. The clinical control rate in study group was significantly higher than that in control group (P <0.05), and the difference was statistically significant. Conclusion: The therapeutic effect of nebulized inhalation on acute asthma in infants and young children is basically the same as that of oral medication. However, the clinical control of nebulized inhalation is better than oral administration, which can relieve the clinical symptoms of patients rapidly and is worth popularizing in clinic.