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自从异菸肼问世以来,其抗结核菌机理比较公认的说法,是因异菸肼能与体内的醛等物质结合形成腙,而醛类里边的吡哆醛又是细菌代谢的必需物之一,所以异菸肼正好是通过与吡哆醛等结合而影响细菌代谢和生长繁殖的。为了进一步掌握使用常规剂量异
Since the advent of isoniazid, its anti-TB mechanism is generally acknowledged because isoniazid binds to aldehydes and other substances in the body to form hydrazones, while pyridoxal in aldehydes is one of the essential bacterial metabolites , So isoniazid just by combining with pyridoxal and other effects of bacterial metabolism and growth and reproduction. In order to further grasp the use of conventional dose-specific