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性激素是由性腺和肾上腺产生或由其他物质转化而来的类固醇激素。类风湿性关节炎(rheumatoid arthritis,RA)是一种以关节内炎症细胞浸润为特点的自身免疫性疾病,女性RA的发病率比男性高。本文综述性激素在RA发生发展中的作用。首先,介绍RA和性激素的概况,横向比较两性间性激素的差异,分析不同性激素对RA发展的影响;其次,纵向比较因患病导致的性激素水平变化情况及性激素失衡的发生机制;进一步分析与性激素相关的RA治疗方法。
Sex hormones are steroid hormones produced by the gonads and adrenal glands or from other substances. Rheumatoid arthritis (RA) is an autoimmune disease characterized by infiltration of inflammatory cells in the joints. The incidence of RA is higher in women than in men. This article reviews the role of sex hormones in the development of RA. First, we introduce the general situation of RA and sex hormones, compare the sex hormones difference between sexes and analyze the effect of different sex hormones on the development of RA. Secondly, compare the changes of sexual hormones and sex hormone imbalance caused by illness; Related RA treatment.