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目的分析慢性萎缩性胃炎患者的消化内科临床治疗方法和临床疗效。方法 76例慢性萎缩性胃炎患者,按照双盲法随机分成对照组和研究组,各38例。对照组患者进行常规治疗,研究组在常规治疗的基础上加用替普瑞酮,对比两组患者的临床疗效、幽门螺杆菌(Hp)转阴率以及治疗后的疾病复发情况。结果研究组患者的临床治疗总有效率94.74%明显高于对照组的78.95%,研究组治疗后Hp转阴率明显高于对照组,研究组复发率为2.63%明显低于对照组的15.79%,组间对比差异有统计学意义(P<0.05)。结论在慢性萎缩性胃炎患者的临床治疗上,替普瑞酮的应用,可有效促进临床疗效和Hp转阴率的提升,降低疾病的复发率,具有良好的临床实用价值。
Objective To analyze the clinical treatment and clinical efficacy of digestive medicine in patients with chronic atrophic gastritis. Methods A total of 76 patients with chronic atrophic gastritis were randomly divided into control group and study group according to double-blind method, with 38 cases in each group. The patients in the control group were treated routinely. The study group was given teprenone on the basis of routine treatment. The clinical efficacy, the negative conversion rate of Helicobacter pylori (Hp) and the recurrence of the disease were compared between the two groups. Results The total effective rate of clinical treatment was 94.74% in study group and 78.95% in control group. The negative conversion rate of Hp in study group was significantly higher than that in control group, the recurrence rate in study group was 2.63%, significantly lower than that in control group (15.79% , The difference between the groups was statistically significant (P <0.05). Conclusion The application of teprenone in clinical treatment of patients with chronic atrophic gastritis can effectively promote the clinical efficacy and Hp conversion rate of negative and reduce the recurrence rate of the disease, has a good clinical value.