论文部分内容阅读
目的探讨产次及其他因素与子宫肌瘤发生之间的关系。方法研究数据来自东风-同济退休职工队列研究。选取队列中有完整资料的14 280名中老年女性为研究对象,采用多因素Logistic回归模型分析产次与子宫肌瘤发生的关系。结果研究对象中子宫肌瘤患病率为15.7%(2 239/14 280)。多因素Logistic回归分析结果显示,与产次为1个的女性相比,产次为2次、3次、4次及以上的女性罹患子宫肌瘤的危险度逐渐降低,OR值分别为0.793(95%CI:0.702~0.897)、0.666(95%CI:0.558~0.794)和0.543(95%CI:0.422~0.700)。子宫肌瘤的患病危险性随着产次的增加而减少。结论多产次可以降低子宫肌瘤发生的风险,在中国女性中多产次可能是子宫肌瘤的保护因素,该研究结果提示产次少的妇女应注意预防子宫肌瘤的发生。
Objective To explore the relationship between birth times and other factors and the occurrence of uterine fibroids. Methodology data from Dongfeng - Tongji retired staff cohort study. A total of 14 280 middle-aged and elderly women with complete information in the cohort were selected as the study objects. Multivariate Logistic regression model was used to analyze the relationship between the birth number and the occurrence of uterine fibroids. Results The prevalence of uterine fibroids in the study subjects was 15.7% (2 239/14 280). Multivariate Logistic regression analysis showed that the risk of uterine fibroids in women with 2-times, 3-times, 4-times or more births gradually decreased compared with women with 1 births, with OR values of 0.793 95% CI: 0.702-0.897), 0.666 (95% CI: 0.558-0.794) and 0.543 (95% CI: 0.422-0.700). The prevalence of uterine fibroids with the increase of production decreases. Conclusions Multiply times can reduce the risk of uterine fibroids, prolificacy in Chinese women may be the protective factor of uterine fibroids, the results suggest that women with fewer births should pay attention to the prevention of uterine fibroids.