芳香化酶抑制剂对绝经后激素受体阳性乳腺癌患者血脂影响的meta分析

来源 :中国高原医学与生物学杂志 | 被引量 : 0次 | 上传用户:hamainini
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目的使用meta法分析芳香化酶抑制剂(AIs)对绝经后激素受体阳性乳腺癌患者血脂的影响。方法通过计算机检索PubMed、Embase数据库筛选相关数据。使用Review Manager 5.3软件分析甾体和非甾体类AIs对绝经后激素受体阳性乳腺癌患者血脂的影响。结果所涉1 5074人中发生血脂异常者4 937人。相比于非甾体AIs,甾体AIs发生血脂异常的风险相对较低(OR=0.83;95%CI:0.77~0.89;P<0.001)。亚组分析发现,相比于非甾体AIs,甾体AIs发生甘油三酯异常的风险
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