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227例在7岁前有哮喘的21岁成年人及50名对照组进行肺功能测验。277例分为4级:W 级:儿童期或青春期有喘鸣史,但在21岁检查前3年内无发作,共113例;X 级:在21岁检查前3年有喘鸣,但3月内无发作,共68例;Y 级:在21岁检查前3月有喘鸣,但不频繁,也不持久,共88例;Z 级:近1年哮喘反复发作,每周1次或更多。肺功能测验包括:肺活量(VC)、残气(RV)、功能残气(FRC)、第1秒最大呼气量(FEV_1),最大呼气中段流速(FEV25～75%)、最大呼气流速容量曲线(MEFV)和肺泡氮冲洗曲线Ⅲ相等,标准运动试验采用活动平板,其速度以脉搏>170/min 为度。在运动后3min,运动停止时,运动后5、10、15min,用 Wright 流速仪测验最大呼气流速(PEFR)。运动后15min,给予2%异丙基肾上腺素雾化吸入,再测定 PEFR。根据 PEFR 增加
227 cases of 21-year-old adults with asthma before age 7 and 50 control group were tested for pulmonary function. 277 cases were divided into 4 grades: Grade W: history of wheezing in childhood or adolescence, but without seizures in the 3 years before the age of 21, a total of 113 cases; Grade X: wheezing in the 3 years before the age of 21 but 3 Month no seizures, a total of 68 cases; Y-class: 21 years of age before the inspection in March had wheezing, but infrequent, not persistent, a total of 88 cases; Z: recurrent asthma in the past year, once a week or More. Pulmonary function tests included vital capacity (VC), residual capacity (RV), functional residual capacity (FRC), maximum expiratory volume in one second (FEV_1), maximum expiratory flow (FEV 25 to 75% Volume curve (MEFV) and alveolar nitrogen flush curve Ⅲ equal, the standard exercise test using the active plate, the speed of pulse> 170 / min for the degree. The maximum expiratory flow rate (PEFR) was measured at 3 min after exercise, at stop, at 5, 10, 15 min after exercise. After exercise 15min, given 2% isoproterenol nebulized inhalation, and then measured PEFR. According to PEFR increase