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目的探讨多灶性和单灶性甲状腺癌临床病理特征和疗效的比较。方法回顾性分析2012年1月至2015年12月间上海市金山区亭林医院收治的458例甲状腺癌患者的病例资料,比较多灶癌组与单灶癌组之间的临床病理特征和疗效的差异。结果与单灶性甲状腺癌相比,多灶性甲状腺癌性别和肿瘤大小方面差异无统计学意义(P>0.05),且常伴桥本甲状腺炎和结节性甲状腺肿,微小癌发生比例高,易发生转移、复发和浸润,愈后较差,但多灶性甲状腺癌患者术后并发症发生率并未明显高于单灶性甲状腺癌患者。结论多灶性甲状腺癌有较强的侵袭性,采用全甲状腺切除术联合中央区淋巴结清扫的术式疗效较好。
Objective To investigate the clinicopathological features and therapeutic effects of multifocal and single focal thyroid carcinoma. Methods The clinical data of 458 cases of thyroid cancer admitted to Tinglin Hospital in Jinshan District of Shanghai from January 2012 to December 2015 were retrospectively analyzed. The clinicopathological characteristics and therapeutic effects The difference. Results There was no significant difference in the gender and tumor size between multifocal thyroid cancer and single thyroid cancer (P> 0.05). Hashimoto’s thyroiditis and nodular goiter often accompanied by a high proportion of micro-cancer , Prone to metastasis, recurrence and infiltration, the worse after the prognosis, but the incidence of postoperative complications in patients with multifocal thyroid cancer was not significantly higher than in patients with single thyroid cancer. Conclusions Multifocal thyroid cancer has strong invasiveness. The use of total thyroidectomy combined with central lymph node dissection is effective.