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目的为了查明流行性出血热（ＥＨＦ）病人血清型与宿主动物血清型关系，探讨血清学演变及其意义。方法采用ＩＦＡ、ＨＩ和ＲＰＨＩ法分型。结果在４５８例病人中，存在家鼠型、野鼠型和未定型病人，分别占９１．４８％、７．２１％和１．３１％。同时检测鼠肺，其中家鼠ＥＨＦ病毒（ＥＨＦＶ）抗原阳性率为６．５８％（１６／２４３），病毒抗原型均为家鼠型。野鼠４份阴性；在鼠血清中，家鼠血清ＥＨＦ抗体阳性率为１０．７１％（４４／４１１），血清型为家鼠型，野鼠阳性率为４．１７％（３／４８），血清型为野鼠型。结论证实当地是以家鼠型为主的家、野鼠型混合型疫区，ＥＨＦＶ抗原型和血清型别均与宿主动物种类相一致。
Objective To find out the relationship between the serotypes of the patients with epidemic hemorrhagic fever (EHF) and the host animal serotypes and to explore the serological changes and their significance. Methods The methods of IFA, HI and RPHI were used. Results Among the 458 patients, there were 91.48%, 7.21% and 1.31% of domestic mice, wild mice and untypical patients, respectively. In the meantime, the positive rate of EHFV antigen in house mouse was 6.58% (16/243). All the virus antigen types were domestic mice. The positive rate of EHF antibody in domestic mice was 10.71% (44/411), and that of domestic mice was 4.17% (3/48) in serogroups. Serum Type for the wild mouse type. Conclusion It is confirmed that there is a house-based home in the local area. The mixed type of encephalitis and the type of EHFV antigen and serotype are consistent with the host animal species.