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任何宫缩抑制剂均有可能阻断已临产的早产,达到治疗早产的目的.宫缩抑制剂目前可分为两类,一类为抑制宫缩减少子宫肌对刺激反应的药物,一类为阻断或抑制前列腺素(PG)合成的药物.治疗早产的药物很多,都是通过抑制子宫收缩使子宫呈松弛状态,或使子宫肌对外来刺激反应性降低,从而减低子宫肌的收缩强度和频率,避免发生早产.1 乙醇能抑制脑垂体生成和释放催产素及抗利尿激素,同时作用于子宫肌层使之松弛,阻止PGF_(2α)的合成和释放,从而抑制子宫收缩.用法:95%乙醇50ml 加入5%葡萄糖450ml 中静脉滴注,开始以每小时7.5ml/kg 的速度滴入,1～2小时后改为每小时1.5ml/kg 静滴(维持量),可持续6～10小时.重复用药应间隔10小时以上.其副作用为恶心、呕吐、多尿、烦躁、头痛等酒精中毒症状.亦可通过胎盘进入胎体,故胎儿血浓度与孕妇血浓度相同,胎儿出生后可能发生精神抑制、呼吸暂停等.由于有效量与中毒量
Any tocolytic agents are likely to block the preterm labor has been reached, to achieve the purpose of treatment of premature delivery.Constituents can now be divided into two categories, one for the inhibition of uterine muscle contractions to stimulate the response of drugs, one for Blocking or inhibiting the synthesis of prostaglandin (PG) drugs.Many drugs for the treatment of preterm labor, are by inhibiting uterine contraction of the uterus was relaxed state, or uterine muscle to reduce the external stimulus response, thereby reducing the contractile strength of the uterine muscle and Frequency, to avoid premature birth.1 Ethanol can inhibit the pituitary gland formation and release of oxytocin and antidiuretic hormone, at the same time act on the myometrium to relax, prevent the synthesis and release of PGF_ (2α), thereby inhibiting uterine contractions. % Ethanol 50ml added to 5% glucose 450ml intravenous drip, began to drip 7.5ml / kg per hour, 1 to 2 hours later changed to 1.5ml / kg intravenous infusion (maintenance), sustainable 6 ~ 10 hours. Repeated medication should be more than 10 hours interval. The side effects of nausea, vomiting, polyuria, irritability, headache and other symptoms of alcoholism. Can also enter the carcass through the placenta, so the serum concentration of fetal blood and pregnant women the same, It may happen God depression, apnea, etc. Since the effective amount of toxic dose