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为观察不同实验动物对藐小棘隙吸虫的易感性 ,以定量囊蚴感染幼犬 2只、幼猫 2只、新西兰兔 3只、昆明小鼠 10只、猪 2头、鸡鸭各 10只 ,并观察犬体内藐小棘隙吸虫成虫寿命、日产虫卵量以及排卵动态。结果所有感染犬、兔、猫均检获成虫 ,10只小鼠有 7只感染成功 ,其他实验动物均为阴性 ;犬、兔、猫和鼠的获虫率分别为 5 6 .15 %、5 1.45 %、2 9.82 %和 11.93%。实验犬和兔的获虫率、所获虫体大小以及虫体子宫含卵数均明显高于或大于实验猫和小鼠。上述结果表明 ,犬和兔是藐小棘隙吸虫适宜终宿主 (其中兔为终宿主新记录 ) ,猫次之 ,小鼠的易感性较低。实验犬感染藐小棘隙吸虫后第 13d开始从粪便中排卵 ,此后排卵量迅速增加 ,感染后 3个月达到高峰 ,感染后 6个月时明显下降 ,10个月时排卵量处于很低水平 ,此后 10个月仍维持同一水平 ,未见明显升降或停止排卵现象。犬体内 13～ 2 5日龄藐小棘隙吸虫成虫日产卵量为 ( 48± 2 7)个。成虫在犬体内的寿命超过 2 0个月。另外 ,3只兔感染日本血吸虫 ( 2 0 0 0尾蚴 /只 ) 2 8d后再用藐小棘隙吸虫囊蚴攻击感染 ,结果对藐小棘隙吸虫产生了明显的抗性 ,与无血吸虫感染的实验兔相比其减虫率达到 86 .78%～ 10 0 % (平均为 92 .0 9% )。藐小棘隙吸虫 /兔模型对于研究异
In order to observe the susceptibility of different experimental animals to Spiraecoidescens, two young puppies, two young kittens, three New Zealand rabbits, ten Kunming mice, two pigs and ten chickens and ducks , And to observe the life span of the adult Spodoptera exigua, the number of eggs per day and the ovulation dynamics. Results All the infected dogs, rabbits and cats seized adults. Seven of 10 mice were infected successfully, and all other animals were negative. The worm-acquisition rates of dogs, rabbits, cats and mice were respectively 56.15% and 5 1.45 %, 2 9.82% and 11.93% respectively. Experimental dogs and rabbits get the worm rate, the size of the parasites obtained and the number of eggs in the uterus were significantly higher than or greater than the experimental cats and mice. The above results show that dogs and rabbits are the appropriate terminal hosts for the small spines, of which the rabbit is the new host of the final record, cats second, the mice less susceptible. Experimental dogs infected with small spines flukes after 13 days began to ovulate from the stool, and then rapidly increased ovulation, 3 months after infection peaked significantly reduced 6 months after infection, ovulation at 10 months at a very low level , After 10 months still maintain the same level, no significant movements or stop ovulation. The daily fecundity of the adult Spodoptera litura adults at 13 ~ 25 days was (48 ± 27) days. Adults in dogs more than 20 months life expectancy. In addition, 3 rabbits infected with Schistosoma japonicum (20 000 cercariae / only) for 28 days and then challenged with Echinococcus pygmaea. The results showed that the three strains of rabbits had obvious resistance to S. japonicum and no schistosome infection Compared with experimental rabbits, the worm reduction rate reached 86.78% ~ 100% (average 92.90%). The small spines fluke / rabbit model for the study different