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于1989—1990年，对海水网箱养殖的云纹石斑鱼自然感染和人工感染的淋巴囊肿病进行电镜观察。观察结果表明，自然感染和人工感染的淋巴囊肿细胞之间并无区别，它们均含有许多包涵体和病毒颗粒；主要描述用患淋巴囊肿病病鱼的皮肤结节匀浆对实验鱼作皮下注射而感染的淋巴囊肿病的超微病理过程，包括病毒颗粒在成纤维细胞胞膜上的附着和成纤维细胞及其内含物的形态变化等过程；此外，病鱼心脏、肝脏、脾脏、肾脏和肠上皮也有不同程度的病理变化。
In 1989-1990, electron microscopy was performed on naturally infected and artificially infected lymphatic cyst of maruped grouper cultured in seawater cages. The observations showed that there was no difference between naturally infected and artificially infected lymphatic cyst cells, both of which contained many inclusion bodies and virus particles. The main purpose of this study was to subcutaneously inoculate the experimental fish with skin nodule homogenate from diseased fish with lymphatic cyst The pathological process of lymphatic cyst disease infection, including the attachment of virus particles in the membrane of fibroblasts and the morphological changes of fibroblasts and their contents; in addition, the disease heart, liver, spleen, kidney And intestinal epithelium also have varying degrees of pathological changes.