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目的:冠状动脉病变是川崎病最严重的并发症,探讨其发生的有关因素有利于及早发现、估计预后、减少冠状动脉病变的危害,改善患儿的预后。方法:回顾2002年~2008年6年间我院收治的131例川崎病患儿进行分组,将发生冠状动脉病变的和未发生冠状动脉病变的2组患儿从性别、年龄、临床表现、实验室检查、诊断治疗、预后等方面入手进行分析及比较。结果:发生与未发生CAL的患儿在C反应蛋白、血沉、血红蛋白水平及免疫活性测定上比较有统计学意义。结论:本文单因素分析表明C反应蛋白明显增高、高血沉是发生CAL的危险因素。
OBJECTIVE: Coronary artery disease is the most serious complication of Kawasaki disease. To explore its related factors is beneficial to early detection, prognosis, reduce the risk of coronary artery disease and improve the prognosis of children. Methods: A total of 131 Kawasaki disease patients admitted to our hospital from 2002 to 2008 were divided into two groups according to gender, age, clinical manifestations, laboratory conditions Inspection, diagnosis and treatment, prognosis and other aspects of the analysis and comparison. Results: Children with and without CAL had statistical significance in the determination of C-reactive protein, erythrocyte sedimentation rate, hemoglobin and immunocompetence. Conclusion: The univariate analysis showed that C-reactive protein was significantly increased, and ESR was a risk factor for CAL.