Reaven在1988年的Banting讲座中创造了“X综合征”一词以描述下列一组异常:对胰岛素促进葡萄糖摄取的抵抗、葡萄糖耐量异常、高胰岛素血症、VLDL甘油三脂水平增高、HDL胆固醇水平降低以及高血压。胰岛素抵抗常见于肥胖、多囊卵巢综合征、糖尿病,红斑狼疮及其他有抗胰岛素受体抗体的自身免疫性疾病,部分或完全性脂肪营养不良、较少见的疾病如矮妖精貌综合征以及其他多 Reaven created the term “Syndrome X” in a 1988 Banting lecture to describe the group of abnormalities: resistance to insulin in promoting glucose uptake, impaired glucose tolerance, hyperinsulinemia, increased levels of VLDL triglycerides, HDL cholesterol Lower levels and high blood pressure. Insulin resistance is commonly found in obesity, polycystic ovary syndrome, diabetes, lupus erythematosus and other autoimmune diseases with anti-insulin receptor antibodies, partial or complete lipodystrophy, and less common diseases such as leprosy syndrome and Many others