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目的观察散结镇痛胶囊联合米非司酮治疗子宫内膜异位症的临床疗效。方法将子宫内膜异位症患者128例以投掷法随机分成观察组和对照组各64例。观察组予散结镇痛胶囊联合米非司酮治疗,对照组口服米非司酮治疗,对比分析2组患者用药后疗效及性激素水平情况。结果观察组总有效率为96.88%高于对照组的67.19%,差异具有统计学意义(χ~2=4.278,P<0.05)。用药前2组患者各性激素水平比较差异无统计学意义(P>0.05);用药后2组患者各性激素水平均有明显降低,且观察组低于对照组,差异均有统计学意义(P<0.05)。结论散结镇痛胶囊联合米非司酮治疗子宫内膜异位症效果明显,可有效缓解患者痛经、肿块等症状,值得广泛推广应用。
Objective To observe the clinical efficacy of Sanjiezhitong capsule combined with mifepristone in the treatment of endometriosis. Methods 128 patients with endometriosis by throwing method were randomly divided into observation group and control group of 64 cases. The observation group was treated with Sanjie analgesic capsule combined with mifepristone, while the control group was treated with mifepristone. The curative effect and sex hormone level of the two groups were compared. Results The total effective rate in observation group was 96.88%, which was significantly higher than that in control group (χ ~ 2 = 4.278, P <0.05). There was no significant difference in the levels of sex hormones between the two groups before treatment (P> 0.05). The levels of sex hormones were significantly decreased in both groups after treatment, and the levels in the observation group were lower than those in the control group (P < 0.05). Conclusion Sanjie analgesic capsules combined with mifepristone treatment of endometriosis has obvious effect, which can effectively alleviate the symptoms such as dysmenorrhea and lumps in patients, which is worth popularizing widely.