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应用荧光分光光度测定法和世界卫生组织推荐的神经行为核心测试组合法分别对汞污染水平不同的地区(大气中汞浓度平均值,污染区为0.0021mg/m3,对照区0.00065mg/m3)非职业性汞接触居民进行尿中去甲肾上腺素、多巴胺、5-羟色胺、5-羟吲哚乙酸4种神经递质含量和神经行为功能测定。结果显示:污染区居民尿中4种神经递质含量均高于对照区居民,两区神经行为功能指标测试值不同,经检验均有显著性差异(P<0.05)。提示汞可以干扰神经递质的代谢过程,并对神经行为功能产生影响。
Application of fluorescence spectrophotometry and the World Health Organization recommended neurobehavioral core test combination of mercury levels in different regions (the average mercury concentration in the air pollution area 0.0021mg / m3, the control area 0.00065mg / m3 ) Non-occupational mercury exposure to inhalation of norepinephrine, dopamine, 5 - hydroxytryptamine, 5 - hydroxyindole acetic acid content of 4 neurotransmitters and neurobehavioral determination. The results showed that the urinary contents of four neurotransmitters in residents in the polluted area were higher than those in the control area. There were significant differences in neurobehavioral indexes between the two districts (P <0.05). It is suggested that mercury interferes with the neurotransmitter metabolism and affects neurobehavioral function.