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目的 观察阿托伐他汀对血脂正常的稳定性心绞痛患者的抗心肌缺血作用。方法 83例血脂正常的稳定性心绞痛患者随机分为治疗组 ( 4 3例 ,加服阿托伐他汀 12个月 )和对照组 ( 4 0例 ,常规治疗 ) ,以平板运动试验等为考察指标。结果 ⑴治疗后 12个月治疗组运动持续时间、至心绞痛发作时间及ST段下降 1mm的时间均明显延长 ,且均高于对照组 (P <0 0 1) ;⑵治疗后 12个月治疗组心绞痛发作次数及缺血相关事件明显低于对照组 (P <0 0 5 )。结论 长期使用阿托伐他汀对血脂正常的稳定性心绞痛患者具有抗心肌缺血作用
Objective To observe the anti-ischemic effects of atorvastatin on patients with stable lipoproteins and stable angina pectoris. Methods Eighty-three stable patients with stable angina pectoris were randomly divided into treatment group (43 cases, atorvastatin for 12 months) and control group (40 cases), and treadmill exercise test . Results (1) The duration of exercise, duration of angina pectoris and ST segment depression by 1 mm were significantly longer in the treatment group than in the control group (P <0.01) at 12 months after treatment. (2) The treatment group The number of angina attacks and ischemic related events were significantly lower than those in the control group (P <0.05). Conclusion Long-term use of atorvastatin has anti-ischemic effects on patients with stable lipoproteins and stable angina