白粉侧孢霉(sporotrichum pruinosum)是土壤和植物中广泛分布的一种腐生真菌,对人体致病的报告极少。本文报告了患有肺、支气管病的3例病人呼吸道中分离出此菌。例1.43岁,女性。诉呼吸困难、咳嗽、咳痰及胸痛20年。1年前患肺炎,曾用支气管扩张剂、抗生素等治疗无效,例2.33岁,男性。打喷嚏、鼻炎、胸痛,咳少量痰及发热2年半,胸透见右下肺野有阴影,例3.45岁,女性。诉自幼反复患感冒,咳嗽、咳痰,有双侧副鼻窦炎,无呼吸困难和哮喘史。胸透于右下、左下及中部肺野反复出现肺炎样病变。患者的新鲜痰液真菌检查结果示,除例2同时伴有烟曲霉感染外,3例均分离出白粉侧孢霉(例1痰培养8次,有4次阳性。例2痰培养10次,5次阳性,另1次吸取支气管分泌物亦培养出此菌。例3痰培养10次,6次阳性),未检出其他致病菌。白粉侧孢霉特征:直接镜检时查到厚壁孢子。在沙氏葡萄糖琼脂 Sporotrichum pruinosum is a saprophytic fungus widely distributed in soil and plant and has very few reports of human pathogenicity. This article reports the lungs, bronchial disease in three patients isolated from the respiratory tract of the bacteria. Example 1.43 years old, female. Suffering from breathing difficulties, cough, expectoration and chest pain for 20 years. A year ago suffering from pneumonia, bronchodilators, antibiotics and other treatment was invalid, for example 2.33 years old, men. Sneezing, rhinitis, chest pain, cough and phlegm and fever for a few years and a half, chest see the right lung field shadow, for example 3.45 years old, female. Suffering from repeated childhood cold, cough, expectoration, bilateral sinusitis, no breathing difficulties and asthma history. Chest through the lower right, lower left and middle lung field repeated pneumonia-like lesions. Fresh sputum of patients with fungal examination results showed that in addition to the case of Aspergillus fumigatus infection in addition to 2 cases, were isolated in 3 cases of Aspergillus pleurotus (Example 1 sputum culture 8 times, there are 4 positive cases of sputum culture 10 times, 5 times positive, the other bronchial secretions were also cultivated this bacterium .Example 3 sputum culture 10 times, 6 times positive), did not detect other pathogens. Aspergillus pleurotus characteristics: direct microscopy found thick-walled spores. On Sabouraud dextrose agar