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目的 :观察再障病人应用维生素B6 (B6)对骨髓及其周围血的影响。方法 :对 12例慢性再障静脉点滴 (40 5 0mg/kg.d)B6 ,疗程 6 0天 ,对比观察治疗前后周围血红细胞、血红蛋白、白细胞、血小板、网织红细胞及骨髓变化情况。结果 :经 6 0天B6治疗后症状明显改善 ,红细胞、血红蛋白、血小板指标上升 ,骨髓缓解率为 75 %。结论 :大剂量B6能够促进骨髓造血功能的恢复 ,是治疗小儿再障的有效药物。
Objective: To observe the effect of vitamin B6 (B6) on bone marrow and its peripheral blood in aplastic anemia patients. Methods: Twelve patients with chronic aplastic anemia were given intravenous drip (40 5 0 mg / kg.d) of B6 for 60 days. The changes of peripheral blood red blood cells, hemoglobin, white blood cells, platelets, reticulocytes and bone marrow were observed before and after treatment. Results: After 60 days, the symptoms of B6 were significantly improved. The indexes of erythrocyte, hemoglobin and platelet increased. The rate of bone marrow remission was 75%. Conclusion: High-dose B6 can promote the recovery of bone marrow hematopoietic function and is an effective drug for the treatment of children with aplastic anemia.