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临床脂质测定并未显示出糖尿病或心血管病相关的脂质代谢改变的复杂性。脂质组学则能够评估可作为疾病风险潜在标志物的数百种脂质种类。方法:纳入来自糖尿病治疗和血管保护行动:强化降压和强化降糖治疗对2型糖尿病高危患者血管疾病预防作用的析因随机研究(the action in diabetes and vascular disease:preterax and diamicron MR controlled evaluation,ADVANCE)的亚组人群(n=3779),应用液相色
Clinical lipid assays do not show the complexities of altered lipid metabolism associated with diabetes or cardiovascular disease. Lipidomics is capable of evaluating hundreds of lipid classes that can be potential markers of disease risk. METHODS: The action in diabetes and vascular disease: preterax and diamicron MR controlled evaluation, enrolled from the Diabetes Care and Vascular Protection Initiatives: Intensified Antihypertensive and Intensive Hypoglycemic Therapy for Prevention of Vascular Disease in High-risk Type 2 Diabetic Patients. ADVANCE) subgroup (n = 3779), using liquid color