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目的通过回顾性分析了解妊娠合并甲状腺功能减退的现患情况,妊娠合并症及妊娠结局对胎儿的影响。方法选取2011年1月-2013年12月于该院进行孕前检查并准备生产的孕妇作为研究对象,其中62例妊娠合并甲状腺功能减退的孕妇作为病例组,按照治疗后促甲状腺激素(TSH)水平浓度将其分为控制组38例和控制不良组24例2个亚组。选取同期入院检查和生产的正常孕妇60例作为对照组。比较分析3组研究对象的临床资料。结果本院妊娠合并甲状腺功能减退的现患率为11.34‰,妊娠期间控制不良组孕妇糖尿病、高血压、妊娠合并子痫和羊水胎粪的发病高于控制组及对照组,3组比较差异有统计学意义(P<0.05);3组新生儿的胎儿缺氧,低体重现象和新生儿甲减情况差异有统计学意义(P<0.05),控制不良组高于对照组。结论妊娠合并甲状腺功能减退发病逐年递增,现患率较高,容易引起妊娠合并症并影响胎儿发育,应该开展和加强育龄妇女及妊娠早期甲状腺功能的筛查工作。
Objective To investigate the effects of pregnancy-related complications and pregnancy outcomes on the fetus by retrospective analysis of the prevalence of pregnancy complicated with hypothyroidism. Methods A total of 62 pregnant women with prenatal examination and preparation for production from January 2011 to December 2013 were enrolled. Among them, 62 pregnant women with pregnancy complicated with hypothyroidism were selected as the cases according to the levels of thyroid stimulating hormone (TSH) The concentration was divided into control group 38 cases and poor control group 24 cases 2 subgroups. Select the same period of hospitalization and inspection and production of 60 normal pregnant women as a control group. Comparative analysis of three groups of clinical data. Results The prevalence of hypothyroidism during pregnancy was 11.34 ‰. The incidence of diabetes mellitus, hypertension, pregnancy-induced eclampsia and meconium-stained amniotic fluid in pregnant women with poor control were higher than those in control and control groups. There were statistically significant differences among the three groups (P <0.05). There was a significant difference in hypoxia, low body weight and neonatal hypothyroidism between the three groups (P <0.05). The control group was higher than the control group. Conclusions The incidence of pregnancy complicated with hypothyroidism increases year by year, and the prevalence is high. It is easy to cause pregnancy complications and affect fetus development. Screening of thyroid function in women of childbearing age and early gestation should be carried out.