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观察了氰胺酮（Ｋｅｔ）与赛拉嗪（Ｘｙ１）以１：１和３：１配伍对小鼠急性毒性和翻正反射消失效应的影响。用Ｑ（ｘ）统计检验合用后的联合作用性质，并绘制出Ｑ曲线及其９５％可信限图．可见Ｋｅｔ与Ｘｙｌ以１：１和３：１伍用后毒性分别为相加和轻微协同，翻正反射消失效应均呈协同性增强．配伍后的治疗指数，安全指数及可靠安全系数都较单药提高．大鼠和大的实验结果也表明Ｋｅｔ与Ｘｙｌ伍用后效应增强．
The effects of 1: 1 and 3: 1 combination of Ket and Xy1 on the acute toxicity and the disappearance of reflex in mice were observed. The Q (x) statistics were used to test the combined effect after combination and the Q curve and its 95% confidence limit were plotted. Visible Ket and Xyl 1: 1 and 3: 1 Wu toxicity after use were additive and slightly synergistic, turn right reflex disappearance effect showed a synergistic enhancement. After the compatibility of the treatment index, safety index and reliable safety factor than monotherapy. Large experimental results in rats and also showed that Ket and Xyl after the use of enhanced effects.