本文报导痛炎速灵片的溶出度及在家兔体内生物利用度。实验表明,片剂的体外溶出参数T_(50)=0.41±0.44min,Td=0.64±0.63min;体内参数,PO片削C_(max)=11.13±2.43μg/mlT_(max)=1.29±0.15hr,AUC~(0→∞)=44.61μg/ml。hr:PO水溶液C_(max)=12.73±2.39μg/ml,T_(max)=1.09±0.38hr,AUC~(0→∞)=50.39±12.88μg/ml。hr;iv.AUC~(0→∞)=82.00±14.48μg/ml。hr;PO片剂的相对生物利用度88.84%,绝对生物利用度54.40% This article reports the dissolution of toxcite tablets and in vivo bioavailability in rabbits. The results showed that the in vitro dissolution parameters of T_ (50) = 0.41 ± 0.44min and Td = 0.64 ± 0.63min, and the in vivo parameters, C_max = 11.13 ± 2.43μg / mlT = 1.29 ± 0.15 hr, AUC ~ (0 → ∞) = 44.61 μg / ml. hr: PO aqueous solution C max = 12.73 ± 2.39 μg / ml, T max = 1.09 ± 0.38 hr, AUC 0 → ∞ = 50.39 ± 12.88 μg / ml. hr; iv. AUC ~ (0 → ∞) = 82.00 ± 14.48 μg / ml. hr; the relative bioavailability of PO tablets was 88.84%, the absolute bioavailability was 54.40%