手足口病,是由多种肠道病毒引起的常见传染病之一,多发于5岁以下儿童,临床表现为发热,手、足、口腔等部位皮疹,部分患儿可发生心肌炎、无菌性脑膜脑炎、肺水肿等严重并发症[1]。虽然只有少数患儿发生上述严重并发症,但是一旦发生,病死率非常高,约80%患儿可在发病后24 h内死亡[2]。重 Hand-foot-mouth disease is one of the common infectious diseases caused by various enteroviruses. It occurs frequently in children under 5 years of age. The clinical manifestations are fever, hand, foot and mouth and other parts of the rash. Some children may develop myocarditis and aseptic Meningoencephalitis, pulmonary edema and other serious complications [1]. Although only a small number of children with these serious complications, but in the event of a very high case fatality rate, about 80% of children can be within 24 hours after onset of death [2]. weight