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阿米妥(Amytal)颈动脉内注射(Wada试验),使一侧大脑半球的功能暂停,从而检验对侧大脑半球“单独存在”时的语言和记忆等功能。这一检查技术首先是Wada于1949年提出的,起初主要用于确定语言优势半球。随后,较多的学者把注意力集中在阿米妥对运动的影响。Milner等(1962)将此项技术用于测定需要手术治疗的癫痫病人大脑半球记忆功能。以避免因手术切除包含癫痫病灶的脑组织而发生术后“完全性遗忘症”(global amnesia)。随后,又有人报导了几种有关语言-记忆功能试验改良的方法。综合国内外众多学者的经验,我们制定了一套检查程序,并对4例需手术治疗的顽固性癫痫病人术前进行了Wada试验。现将其结果报道如下,并对其临
Amytal intracarotid injection (Wada test) halted the function of one hemisphere on one side and examined the function of speech and memory in the contralateral hemisphere “alone”. This inspection technique was first proposed by Wada in 1949, initially primarily for determining the dominant hemisphere of language. Subsequently, more scholars focused their attention on the impact of amiodar on exercise. Milner et al. (1962) used this technique to determine the hemispheric memory function in patients with epilepsy requiring surgery. To avoid postoperative “global amnesia” due to surgical removal of brain tissue containing epileptic lesions. Subsequently, there were several reports on the language - memory function test improved method. Based on the experience of many scholars at home and abroad, we developed a set of inspection procedures and carried out Wada test on 4 patients with intractable epilepsy who need surgery. The results are reported below, and its immediate