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本文观察了54例单纯口腔扁平苔藓(OLP)男女患者,发现患者组在负性生活事件分、总生活事件分、SAS和SDS积分上显著高于健康人对照组,同时患者组还存在T细胞亚群平衡紊乱、口腔粘膜微循环(OMC)障碍。糜烂型病根较重OLP患者组在焦虑程度、CD+8细胞数百分率和OMC综合积分等项目上显著高于非糜烂型病根较轻OLP患者组。提示心理应激与OLP疾病密切相关,T细胞亚群功能和OMC障碍程度与OLP病损相关。
In this study, we observed 54 male and female patients with simple oral lichen planus (OLP) and found that patients in the group of negative life events, total life events, SAS and SDS scores were significantly higher than the healthy control group, while patients also had T cells Subpopulation balance disorders, Oral mucosal microcirculation (OMC) disorders. Erosive disease root heavier OLP patients in the group of anxiety, CD 8 cell percentage and OMC comprehensive score and other items was significantly higher than the non-erosive diseased root OLP patients. Tip psychological stress and OLP disease is closely related to T cell subsets function and degree of OMC disorders and OLP lesions related.