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药物体外試驗的特点主要在于經济、迅速,并可直接观察到药物对虫体的作用情况,达到初篩的目的,且可借此探索药物作用的机轉等。虽然虫体在体外培养液中受到药物的作用,与虫体在体內受到药物的作用不一样,因而体外药物試驗不能完全肯定某种药物在体內是否有效,但这并不排除这种試驗結果的参考价值。在研究药物对某种寄生蠕虫的影响时,最好将該蠕虫放在合适的培养液中,液內含有无机盐和一些营养物质,并維持适当的渗透压、PH值和溫度,必要时可加入对虫体无害的抗菌素,以免微生物同时繁殖。一般說来,培养液最好与其体內寄生部位的环境近似,使正常虫体
The main features of drug in vitro tests are economic, rapid, and can directly observe the role of drugs on parasites, to achieve the purpose of screening, and to explore the mechanism of drug action and so on. Although the parasites in the in vitro culture medium by the role of drugs, and the role of the body in the body by the drug is not the same, so in vitro drug testing can not be completely sure whether a drug is effective in the body, but this does not rule out the test The reference value of the result. In studying the effect of a drug on a parasitic worm, it is best to place the worm in a suitable culture medium containing inorganic salts and some nutrients and to maintain the appropriate osmotic pressure, pH and temperature, if necessary Add antibiotics that are harmless to the worms to prevent the microorganisms from multiplying at the same time. In general, the culture fluid is best with the environment similar to its parasitic body parts, so that normal parasites