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目的 探讨大肠息肉大小、形态、病理特征等与息肉恶变的关系。方法 用电子结肠镜对 2 16例大肠息肉进行 2～ 7年内镜随访 ,并对内镜、病理资料进行分析。结果 息肉总癌变率 9.7%。绒毛腺瘤、混合腺瘤癌变率较高 ,二者间有显著性差异 (P <0 .0 5 ) ;管状腺瘤、炎性息肉、增生性息肉癌变率较低 ,与前二者相比有非常显著性差异 (P <0 .0 1)。息肉基底愈宽、愈短 ,癌变率愈高 ,息肉 >2 .0cm者达 2 8.6 % ,广基者达 2 2 .9%。腺瘤性息肉作内镜下摘除术与未作摘除者癌变率有非常显著性差异 (P <0 .0 1)。结论 腺瘤性息肉是癌变高危因素之一。腺瘤体积大 ,呈绒毛状结构者易癌变。息肉不论大小应尽可能予以摘除
Objective To investigate the relationship between the size, morphology, pathological features of colorectal polyps and malignant transformation of polyps. Methods Two to sixteen cases of colorectal polyps underwent endoscopic follow-up with electronic colonoscopy, and the endoscopic and pathological data were analyzed. Results The total canceration rate of polyps was 9.7%. Villous adenoma, mixed adenocarcinoma higher rate of cancer, there was a significant difference between the two (P <0. 05); tubular adenoma, inflammatory polyps, low proliferative polyps canceration rate, compared with the former two There was a significant difference (P <0.01). The wider and shorter polyp basement, the higher the rate of canceration, polypoid> 2.0cm, up to 22.6%, wide base of up to 22.9%. Adenomatous polyps for endoscopic resection and non-removal of cancerous rate has a very significant difference (P <0.01). Conclusion Adenomatous polyp is one of the risk factors of cancer. Adenoma bulky, villous structure easily carcinogenic. Polyps, regardless of size, should be removed as much as possible