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目的:探讨沙丁胺醇联合布地奈德氧驱动雾化吸入治疗高海拔地区小儿喘憋性肺炎的临床疗效。方法:将我院2012年1月—2014年1月收治的46例喘憋性肺炎患儿随机分为沙丁胺醇联合布地奈德氧驱动雾化吸入治疗组和布地奈德氧驱动雾化吸入对照组,治疗组在常规综合治疗的基础上加用沙丁胺醇溶液联合布地奈德混悬液氧驱动雾化吸入,对照组采用常规综合治疗加用布地奈德氧驱动雾化吸入,比较两组在咳嗽消失、气喘缓解、哮鸣音消失、湿啰音消失及住院时间方面的差异。结果:治疗组在缓解气喘、咳嗽消失、肺部哮鸣音消失、缩短住院时间及总有效率方面明显优于对照组,差异有显著性(P<0.01)。结论:沙丁胺醇联合布地奈德氧驱动雾化吸入是治疗高海拔地区小儿喘憋性肺炎的有效方法,并能缩短病程及住院时间,临床疗效显著。
Objective: To investigate the clinical efficacy of salbutamol combined with budesonide oxygen driven atomization inhalation in the treatment of asthmatic pneumonia in children at high altitude. Methods: Forty-six children with asthmatic pneumonia admitted to our hospital from January 2012 to January 2014 were randomly divided into salbutamol combined with budesonide oxygen-driven inhalation therapy group and budesonide oxygen-driven inhalation control group , The treatment group was treated with inhalation of salbutamol combined with budesonide suspension on the basis of conventional comprehensive treatment with inhalation of aerosol, the control group was treated with inhalation of budesonide oxygen by conventional combined therapy, and the two groups were compared in terms of cough disappeared , Asthma relief, disappearance of wheeze, loss of wet rales and length of stay. Results: The treatment group was significantly better than the control group in relieving asthma, cough disappeared, disappearance of lung wheeze, shortening hospital stay and total effective rate (P <0.01). Conclusion: Salbutamol combined with budesonide oxygen inhalation is an effective method to treat infantile asthmatic pneumonia in high altitude areas, and can shorten the course of disease and hospital stay, with significant clinical effects.