持续性异位妊娠(PEP)是保守性手术后最常见的并发症,是由于手术时未将滋养细胞组织完全去除使其继续生长。术后监测β-hCG可帮助尽早诊断,术后预防性应用氨甲喋呤(MTX)可明显减少PEP的发生率。应根据PEP患者的临床症状、hCG变化来选择具体的治疗方法,如化疗、手术和期待疗法。综述PEP的诊断和治疗进展。 Persistent ectopic pregnancy (PEP) is the most common complication after conservative surgery due to the fact that the trophoblast tissue is not completely removed during surgery and continues to grow. Postoperative monitoring of β-hCG can help early diagnosis, postoperative prophylactic methotrexate (MTX) can significantly reduce the incidence of PEP. Patients should be based on the clinical symptoms of PEP, hCG changes to select the specific treatment methods, such as chemotherapy, surgery and expectant therapies. Review of PEP diagnosis and treatment progress.