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最近已证实使用前列腺素合成抑制剂治疗月经过多及因节育器引致的月经失血过多是有效的。作者在带器出血妇女比较了抗溶纤维蛋白制剂—凝血酸(Tranexamic acid TA)和前列腺素合成抑制剂-二氯苯胺苯乙酸钠,(Diclofenac sodiumDS)治疗月经失血过多的效果。31名带器妇女由于月经出血严重要求治疗。经测定月经血量证明17名妇女失血量高于80ml。另4名为70~80ml。19名妇女中18名使用含铜节育器已至少一年,1名妇女使用惰性节育器10年。对19名妇女进行了连续5个月经周期的研究,2个周期口服 TA1.5g 每日三次,连续5天;2个周期是一
It has recently been demonstrated that the use of prostaglandin synthesis inhibitors to treat menorrhagia and excessive menstruation due to an IUD is effective. The authors compared the effects of anti-fibrinolytic agent Tranexamic acid TA and prostaglandin synthesis inhibitor Diclofenac sodium DS in the treatment of excessive menstrual blood loss in women with haemorrhage. 31 women with a severe menstrual bleeding require treatment. The menstrual blood determined by the 17 women show that blood loss is higher than 80ml. The other 4 is 70 ~ 80ml. 18 out of 19 women have used IBRs for at least one year and 1 woman has used IUDs for 10 years. A total of 19 women were studied for 5 menstrual cycles. TA1.5g was orally administered three times daily for 5 consecutive days in 2 cycles. The 2 cycles were one