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妊娠早期测定血清β-人绒毛膜促性腺激素(β-hCG)对体外受精病人的妊娠结果有重要预测价值。研究目的是确定单次于孕早期测定hCG水平对妊娠结果的预报价值及母亲年龄对妊娠结局的影响。对洛杉矶大学生殖中心1988年8月～1990年7月用克罗米芬、人绝经期促性腺激素(hMG)或自然周期宫内授精(IUI)或定时性交或杯授精等治疗结果进行回顾性分析。获妊娠结果的74例(总数的80%)已得到孕早期血清hCG定量测定,其中35例(47%)是在授精后16,17或18天测定的。当时这35例病人均无早孕症状,但得到了每例妊娠的最后结果。hCG是用免疫放射定量测定法。授精后5周
Determination of serum β-human chorionic gonadotropin (β-hCG) in early pregnancy has important predictive value for pregnant women with in vitro fertilization. The purpose of the study was to determine the effect of a single preimplantation determination of hCG levels on the outcome of pregnancy and the impact of maternal age on pregnancy outcome. The University of Los Angeles Reproductive Center from August 1988 to July 1990 with clomiphene citrate, human menopause gonadotropin (hMG) or natural period intrauterine insemination (IUI) or timing of sexual intercourse or cup insemination and other treatment results were retrospectively analyzed. Seventy-four pregnancies (80% of the total) had a pregnant hCG serum level in the first trimester, of which 35 (47%) were measured at 16, 17, or 18 days after insemination. At that time these 35 patients had no symptoms of pregnancy, but the final result of each pregnancy was obtained. hCG is immunoradiometric assay. Five weeks after insemination