Because there is no curative treatment for spinal cord injury,establishing an ideal animal model is important to identify injury mechanisms and develop therapies for individuals suffering from spinal cord injuries.In this article,we systematically review and analyze various kinds of animal models of spinal cord injury and assess their advantages and disadvantages for further studies. Because there is no curative treatment for spinal cord injury, establishing an ideal animal model is important to identify damage mechanisms and develop therapies for individuals suffering from spinal cord injuries. In this article, we systematically review and analyze each kinds of animal models of spinal cord injury and assess their advantages and disadvantages for further studies.