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目的探讨心力衰竭患者动态血压参数对心力衰竭分级及颈动脉内膜厚度检测的意义。方法选取初诊心力衰竭患者82例作为研究对象,依据患者心功能分级,将其分为A组40例和B组42例。A组患者心功能Ⅱ级,B组患者心功能Ⅲ级和Ⅳ级。对2组患者进行动态血压监测,并进行超声心动图检查和颈动脉检查。此外颈动脉中—内膜增厚患者共55例,非增厚者27例,对2组患者的生化指标进行检测和比较。结果 A组24 h平均收缩压、24 h平均舒张压、白昼平均收缩压、白昼平均舒张压、夜间平均收缩压、夜间平均舒张压、24 h收缩压标准差和24 h舒张压标准差均显著高于B组,非勺型动态血压节律率显著低于B组(P均<0.01);颈动脉中—内膜增厚患者24 h平均收缩压、24 h平均舒张压、白昼平均收缩压、白昼平均舒张压、夜间平均收缩压、夜间平均舒张压、24 h收缩压标准差和24 h舒张压标准差、非勺型动态血压节律率均高于非增厚患者(P<0.01或P<0.05)。结论心力衰竭患者中心功能受损越严重,则其动态血压参数异常性越高,且其颈动脉中—内膜增厚发生率也较高,研究价值显著。
Objective To investigate the significance of ambulatory blood pressure parameters in patients with heart failure on the classification of heart failure and carotid intima-media thickness. Methods 82 cases of newly diagnosed heart failure patients were selected as the research object. According to their cardiac function classification, 40 cases were divided into A group and 42 cases in B group. A group of patients with cardiac function grade Ⅱ, B group of patients with cardiac function grade Ⅲ and Ⅳ. Ambulatory blood pressure monitoring was performed on 2 groups of patients and echocardiography and carotid artery examination were performed. In addition, 55 cases of carotid intima-media thickness and 27 cases of non-thickening were examined. The biochemical indexes of two groups were detected and compared. Results The average systolic blood pressure at 24 hours, mean diastolic blood pressure at 24 hours, mean systolic blood pressure at daytime, mean diastolic blood pressure at daytime, mean systolic blood pressure at night, mean diastolic blood pressure at night, systolic blood pressure at 24 hours and standard deviation at 24 hours were significantly higher in group A Higher than group B, non-scooping dynamic blood pressure rhythm rate was significantly lower than that of group B (P <0.01); 24 h mean systolic blood pressure, 24 h mean diastolic blood pressure, average daytime systolic blood pressure, The mean daytime diastolic blood pressure, nighttime average systolic blood pressure, nighttime mean diastolic blood pressure, 24 h systolic blood pressure standard deviation and 24 h diastolic blood pressure standard deviation were higher than those in non-thickened patients (P <0.01 or P < 0.05). Conclusions The more severe central dysfunction of heart failure patients, the higher the anomalous dynamic blood pressure parameters, and the higher incidence of carotid intima-media thickness, the research value is significant.